Category: Weight Management

  • The Weight of Mental Wellness: Exploring the Intertwined Relationship Between Obesity and Mental Health

    The Weight of Mental Wellness: Exploring the Intertwined Relationship Between Obesity and Mental Health

    By Andrew Hewitt, PMHNP

    Introduction

    Obesity, defined as a body mass index (BMI) of 30 or higher, is a complex and chronic disease affecting millions worldwide. While the physical health consequences of obesity, such as cardiovascular disease, diabetes, and certain cancers, are well-documented, the profound impact on mental well-being is often overlooked. As a Psychiatric Mental Health Nurse Practitioner-Board Certified (PMHNP-BC), I frequently observe the intricate connection between obesity and mental health disorders in my clinical practice. This blog post aims to delve into the bidirectional relationship between these conditions, exploring the psychological mechanisms involved and highlighting the importance of integrated care for individuals struggling with both obesity and mental health challenges.

    The Bidirectional Relationship: A Cycle of Distress

    The relationship between obesity and mental health is not simply a matter of one causing the other; rather, it is a complex, bidirectional interplay. Obesity can contribute to the development or exacerbation of mental health disorders, and conversely, mental health conditions can increase the risk of obesity.

    1. Mental Health Disorders Contributing to Obesity:

    • Depression: Depressive symptoms, such as low energy, reduced motivation, and changes in appetite, can lead to decreased physical activity and increased consumption of calorie-dense, comfort foods. Furthermore, certain antidepressant medications may contribute to weight gain (McIntyre et al., 2022).
    • Anxiety Disorders: Individuals with anxiety disorders may use food as a coping mechanism to manage stress and emotional distress. This can lead to overeating and weight gain. Additionally, avoidance behaviors associated with anxiety can limit engagement in physical activity.
    • Bipolar Disorder: Mood stabilizers and antipsychotic medications commonly used in the treatment of bipolar disorder can contribute to weight gain. Moreover, impulsive behaviors during manic episodes may lead to unhealthy eating patterns (Vieta et al., 2023).
    • Post-traumatic Stress Disorder (PTSD): Trauma survivors may experience emotional dysregulation and use food as a means of self-soothing. Hyperarousal and sleep disturbances associated with PTSD can also disrupt healthy eating and activity patterns.
    • Eating Disorders: While seemingly contradictory, some eating disorders, such as binge eating disorder (BED), are characterized by recurrent episodes of consuming large amounts of food in a short period, leading to weight gain and obesity.
    • Schizophrenia: Individuals with schizophrenia are at increased risk for obesity due to factors such as medication side effects, sedentary lifestyles, and limited access to healthy food options (Correll et al., 2022).

    2. Obesity Contributing to Mental Health Disorders:

    • Body Image Dissatisfaction and Low Self-Esteem: Societal stigma surrounding obesity can lead to feelings of shame, guilt, and body dissatisfaction. These negative emotions can contribute to low self-esteem and depression.
    • Social Isolation and Discrimination: Individuals with obesity may experience social isolation, discrimination, and stigmatization, which can lead to feelings of loneliness, rejection, and social anxiety.
    • Physiological Changes: Obesity can lead to physiological changes, such as chronic inflammation and hormonal imbalances, which have been linked to an increased risk of depression and anxiety.
    • Sleep Disturbances: Obesity is associated with sleep apnea and other sleep disorders, which can contribute to mood disturbances, fatigue, and cognitive impairment.
    • Reduced Quality of Life: The physical limitations and health complications associated with obesity can significantly impact quality of life, leading to feelings of frustration, helplessness, and depression.

    Psychological Mechanisms Involved

    Several psychological mechanisms contribute to the intertwined relationship between obesity and mental health:

    • Emotional Regulation: Food can serve as a powerful tool for emotional regulation. Individuals may turn to food to cope with stress, anxiety, sadness, or boredom.
    • Reward Pathways: Overconsumption of highly palatable foods can activate the brain’s reward pathways, leading to addictive-like behaviors and difficulty controlling food intake.
    • Cognitive Distortions: Negative self-talk, distorted body image, and perfectionistic thinking can contribute to unhealthy eating patterns and low self-esteem.
    • Learned Behaviors: Childhood experiences, cultural influences, and family dynamics can shape eating habits and attitudes towards food and body weight.
    • Stress Response: Chronic stress can lead to increased cortisol levels, which can promote abdominal fat storage and contribute to unhealthy eating behaviors.

    The Importance of Integrated Care

    Addressing the complex interplay between obesity and mental health requires a comprehensive, integrated approach that considers both physical and psychological factors.

    • Collaborative Care: Collaboration between primary care physicians, mental health professionals, dietitians, and exercise specialists is essential for providing holistic care.
    • Mental Health Assessment and Treatment: Individuals with obesity should be screened for mental health disorders, and appropriate treatment, such as psychotherapy and medication management, should be provided.
    • Lifestyle Interventions: Lifestyle interventions, including dietary changes, increased physical activity, and behavioral therapy, can help individuals achieve and maintain a healthy weight.
    • Cognitive Behavioral Therapy (CBT): CBT can help individuals identify and modify negative thought patterns and behaviors that contribute to unhealthy eating habits and low self-esteem.
    • Mindfulness-Based Interventions: Mindfulness-based interventions can help individuals develop greater awareness of their eating habits and emotional triggers, promoting healthier coping mechanisms.
    • Motivational Interviewing: Motivational interviewing can help individuals explore their ambivalence about weight loss and develop intrinsic motivation for change.
    • Pharmacological Interventions: In some cases, medication may be used to treat both obesity and mental health disorders. It is important to carefully consider the potential benefits and risks of medication, as well as the potential for drug interactions.
    • Addressing Stigma: Healthcare providers should be aware of and address the stigma surrounding obesity and mental health disorders. Creating a safe and supportive environment can encourage individuals to seek help and engage in treatment.
    • Focus on Health at Every Size (HAES): The HAES approach emphasizes health and well-being regardless of body size. It promotes healthy behaviors, such as nutritious eating and regular physical activity, without focusing on weight loss as the primary goal.

    Conclusion

    The relationship between obesity and mental health is complex and multifaceted. Recognizing the bidirectional nature of this relationship is crucial for providing effective and compassionate care. As a PMHNP-BC, I am committed to advocating for integrated care that addresses both the physical and mental health needs of individuals struggling with obesity. By promoting healthy lifestyles, addressing mental health disorders, and challenging societal stigma, we can empower individuals to achieve optimal well-being.

    Bibliography

    Correll, C. U., Solmi, M., Veronese, N., Bortolato, B., Rosson, S., Santonastaso, P., … & Fornaro, M. (2022). Prevalence of overweight and obesity in schizophrenia, bipolar disorder, and major depressive disorder: a systematic review and meta-analysis. World Psychiatry21(3), 392-413.

    McIntyre, R. S., Jerrell, J., Kennedy, S. H., Patel, K., & Woldeyohannes, H. O. (2022). Weight gain and metabolic disturbance in patients with major depressive disorder: a review of current evidence and clinical implications. Expert Opinion on Drug Safety21(1), 121-133.

    Vieta, E., Berk, M., Schulze, T. G., Carvalho, A. F., Suppes, T., Calabrese, J. R., … & Yatham, L. N. (2023). Bipolar disorders. Nature Reviews Disease Primers9(1), 1-24.

  • The Pros and Cons of Glucagon-like Peptide-1 (GLP-1) Therapy

    The Pros and Cons of Glucagon-like Peptide-1 (GLP-1) Therapy

    In recent years, glucagon-like peptide-1 (GLP-1) receptor agonists have become a potential drug for weight management. As a board-certified Psychiatric Mental Health Nurse Practitioner (PMHNP-BC), I often see people who are having trouble managing their weight along with their mental health problems. As a result, I know that they are very effective at helping people with type 2 diabetes mellitus (T2DM) lose weight and better control their blood sugar levels [1]. However, GLP-1 drugs can cause side effects, just like any other medicine. This blog post aims to give an overview of GLP-1 treatment, including how it can help people lose weight and what side effects they should be aware of.

    Understanding Glucagon-like Peptide-1 (GLP-1) Therapy

    GLP-1 is an incretin hormone that is naturally made by L cells in the gut. It is very important for keeping blood sugar levels steady because it stops glucagon from being released after a meal and increases insulin release [2]. GLP-1 also makes you feel full and decreases your hunger, which helps you eat fewer calories and lose weight.

    GLP-1 Receptor Agonists to Help You Lose Weight

    At least two weight-related health problems, like T2DM or dyslipidemia, must be present along with an obesity body mass index (BMI) of 30 kg/m2 or higher, or an overweight BMI of 27 kg/m2 or higher [1]. Several GLP-1 receptor agonists have been cleared by the FDA to help adults with their weight. By binding to GLP-1 receptors, these drugs imitate the effects of natural GLP-1. This makes you feel full, lowers your hunger, and slows down the emptying of your stomach.

    How GLP-1 therapy can Help you Lose Weight

    Studies have shown that GLP-1 receptor agonists are very good at helping people control their weight. Clinical studies showed that people who took these medicines lost a lot more weight than people who took a placebo [1]. Besides these benefits, GLP-1 treatment may also have the following advantages:

    Better control of blood sugar in people with T2DM

    Lower blood pressure Higher risk factors for heart disease

    Possible benefits for controlling your mood and emotions (not much research is published)

    What Happens When You Take GLP-1?

    Even though GLP-1 treatment can help you lose weight in a big way, it’s important to know about the possible side effects. Most side effects have to do with the digestive system (GI) and usually happen during the first few weeks or months of treatment. This is because the body gets used to the medicine [2]. Some of these GI side effects are:

    • Sickness
    • Spilling
    • Having diarrhea
    • Gas and bloating
    • Pain in the abdomen
    • Having gas
    • Sometimes, medicines that contain GLP-1 can lead to more dangerous side effects, like
    • Pancreatitis that is very rare
    • Reactions caused by allergies
    • GI troubles (like diarrhea and constipation) caused by cholecystokinin (CCK)
    • Rocks in the gallbladder

    Things to Think About When Choosing a Healthcare Provider to Support Your Weight Loss

    We must take care of people who are on GLP-1 therapy. Some important things to think about are:

    Choose the Right Patients: Before starting GLP-1 treatment, carefully check each patient for possible risks and why they shouldn’t be treated. This includes a full medical history, a physical check, and a look for any possible GI problems.

    Teaching the Patient: Tell your patients about the possible side effects of GLP-1 medications and give them ways to deal with them, like making changes to their food and staying hydrated.

    Closely watch patients during treatment, especially in the beginning, to check for side effects and make sure they take their medicine as prescribed.

    Work together with other health care professionals, like primary care doctors and registered dietitians, to make sure that people on GLP-1 therapy get all the care they need.

    In Conclusion

    GLP-1 receptor agonists are useful for helping people who are overweight or obese and dealing with other health problems linked to their weight loss. However, knowing about possible side effects and communicating with your provider as you are being treated is very important. As PMHNP-BCs, we help patients have better outcomes by carefully choosing who should receive GLP-1 therapy, teaching and supporting them and working with other medical workers.

    References

    [1] American Diabetes Association. (2023). Standards of medical care in diabetes—2023. Diabetes Care, 46(Suppl 1), S1-S237. https://diabetes.org/newsroom/american-diabetes-association-2023-standards-care-diabetes-guide-for-prevention-diagnosis-treatment-people-living-with-diabetes

    [2] Drucker, D. J., & Kaufman, F. R. (2016). Glucagon-like peptide-1 receptor agonists for type 2 diabetes mellitus. The New England Journal of Medicine, 375(24), 2381-2392.